Abstract: Chronic pain is a painful condition defined by its duration where pain persists three months or more. Pain is connected with the high price of health care, work inability and disability. Moreover, it has significant consequences for patients and their families, working organizations and the society as a whole. The prevalence of chronic pain...
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Headache in Patients With Covid-19 Infection
Published in Headache TAKE-HOME MESSAGE Chiropractic physicians board certified in neurology and pain management often manage patients with headache, are essential healthcare workers and are engaged in the fight against Covid-19 and co-morbid presentations.The authors summarize current literature regarding headache and Covid-19 and note that headache is a common complaint of patients presenting with acute...
Migraine as a Cortical Brain Disorder
TAKE-HOME MESSAGE Migraine has been a difficult condition to fully understandAdvanced neuroimaging data and neurophysiological research indicate that fluctuating excitability, plasticity, and metabolism of cortical neurons represent the pathophysiological substrate of the migraine cycle.Migraine disorder stems, in part, from an imbalance in inhibitory/excitatory cortical circuitsSpinal Manipulative Therapy (SMT) has been found to have an effect...
The role of structure and function changes of sensory nervous system in intervertebral disc-related low back pain
Summary:Low back pain (LBP) is a common musculoskeletal symptom, which can be developed in multiple clinical diseases. It is widely recognized that intervertebral disc (IVD) degeneration (IVDD) is one of the leading causes of LBP. However, the pathogenesis of IVD-related LBP is still controversial, and the treatment means are also insufficient to date. In recent...
Melatonin for Acute Treatment of Migraine in Children and Adolescents: A Pilot Randomized Trial
AbstractObjectiveTo determine what dose of melatonin is most effective for treating migraine acutely in children and adolescents.BackgroundAcute migraine medications may not work for all patients and may cause side effects. Melatonin is effective for migraine prevention in adults and has been used acutely for procedural pain in children. Our goal was to determine whether a...
Neurological Complications Associated with the Blood-Brain Barrier Damage Induced by the Inflammatory Response During SARS-CoV-2 Infection
AbstractThe main discussion above of the novel pathogenic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has focused substantially on the immediate risks and impact on the respiratory system; however, the effects induced to the central nervous system are currently unknown. Some authors have suggested that SARS-CoV-2 infection can dramatically affect brain function and exacerbate...
Associations of Psychologic Factors with Multiple Chronic Overlapping Pain Conditions
Aims: To characterize psychologic functioning across five chronic overlapping pain conditions (COPCs)-temporomandibular disorders, fibromyalgia, low back pain, headache, and irritable bowel syndrome-and their overlaps.Methods: Participants were 655 adults in the OPPERA study. Psychologic variables were standardized in separate logistic regression models to compare their relative strength of association with each COPC. Random forest regression was...
Dietary Vitamin E Intake Was Inversely Associated with Hyperuricemia in US Adults: NHANES 2009–2014 — Implications for gout management?
Introduction: Current evidence on the association between dietary vitamin E intake and hyperuricemia risk is limited and conflicting. Objective: The aim of the study was to assess the association of dietary vitamin E intake with hyperuricemia in US adults. Methods: We conducted a cross-sectional study using data from the National Health and Nutrition Examination Survey,...
The Cost-Effectiveness of Platelet-Rich Plasma Compared With Hyaluronic Acid Injections for the Treatment of Knee Osteoarthritis
Although a series of either PRP ($8,635.23/QALY) or HA ($5,331.75/QALY) injections for the treatment of symptomatic knee osteoarthritis would be considered cost-effective (cost per QALY < $50,000), PRP injections were not more cost-effective than HA injections. However, PRP was significantly more effective at 1 year, and being associated with an incremental cost-effectiveness ratio of $12,628.15/QALY...
Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China
Take Home Message 36.4% of patients with Covid-19 exhibit neurological symptoms. Chiropractic neurologist should be vigilant when examining patients with headache, dizziness, impaired smell and taste, impaired vision, musculoskeletal pain and nerve pain. When examining patients even without fever, consider Covid-19 as a possible cause of the patients problem. Abstract Importance The outbreak of coronavirus disease...